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These timelines are intended to allow the effects of prescription medications or herbal supplements to dissipate, thereby minimizing the risk of these substances during surgical procedures

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patients with these conditions require careful prescriber assessment before considering therapy Mitochondrial disorders : Might theoretically respond differently to NAD+ supplementation, but clinical evidence is lacking Chronic inflammatory conditions : May have altered NAD+ metabolism, but specific dosing implications are unknown Potential medication interactions have been proposed based on mechanistic understanding, but clinical significance remains unclear