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The Zepbound prescribing information reports similar findings
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Therapeutics and Clinical Risk Management, 16 , 1047-1055
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Likewise, the highly proliferative subcutaneous xenograft model of tumors has a very high EPR effect and could provide a false imprint for nanocarrier-mediated therapeutic options that rely on EPR-mediated passive targeting, moreover, there is a limited availability of patient-oriented research data for this unique phenomenon along with its effect on drug aggregation inside the tumor [104]
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