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Description

TGF- pathway activation occurs with upregulation of TGF- superfamily genes for tissue repair, while simultaneously suppressing pathological TGF-1 secretion in fibrotic conditions

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doi: 10.1097/MOP.0000000000000505

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When the dose goes up, especially across the 3- to 7-mg step, check the mood actively rather than waiting for the patient to raise it

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