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More so, it produces bile acid which is released to help to break down fats in the small intestine and allows the gallbladder to secrete bile

32,43 Moreover, because of the heterogeneous nature of tumors, there are considerable variations in NADPH-related processes in different tumors, for example, the main pathways of glutamine metabolism in the context of PDAC are different from the previous prevailing view as informed by studies of other cancers, 159,192 indicating the need for careful analyses of individual characteristics among cancers for establishing individualized precision therapy

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Acknowledgments This work was supported in part by the Japan Study Group of NAFLD (JSG-NAFLD, Kyoto, Japan)

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