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Amycretin = a unimolecular dual agonist targeting GLP-1 AND amylin receptors

Contrary to this, intraperitoneal administration of GLP-1 agonists does not stimulate vagal afferents 33 , only a small subset of GLP-1R-expressing vagal afferents innervate the intestinal mucosa where GLP-1 cells reside 33,34 , and ablation of vagal GLP-1R neurons doesnt prevent GLP-1Rs satiating effects 35

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(3) Ionescu M, Frohman LA

Debo recordar que mi cuerpo produce naturalmente la cantidad de L- carnitina que necesita y que solo sus excedentes pasan a nivel intestinal, en donde sirven de alimento a cierto tipo de microflora que al metabolizarla genera el residuo perjudicial TMAO