GLP-1s are powerful medications, and many users experience side effects including nausea, constipation, stomach pain, and reflux that can result in a drastically reduced food intake and rapid weight loss
Major trials including SUSTAIN-6 and STEP demonstrate that GLP-1 receptor agonists reduce cardiovascular events and mortality in people with diabetes or obesity
This suggests that the hair loss is not strictly dose-dependent in a linear way but rather connected to the metabolic changes that all therapeutic doses trigger, including significant weight loss with tirzepatide
was supported by an American Diabetes Association Womens Health Career Development Award (9-24-JDFWH-01), a MGH Physician-Scientist Development Award, and the National Institutes of Health COURAGE grant (U24 DK132733)
Appropriate weighted statistical tests were used for comparison of outcomes post IPTW, including weighted chi-square tests for categorical variables, and weighted t tests (mean) for continuous variables

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