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doi: 10.1038/s41467-018-07598-9 513 HartwigJSotznyFBauerSHeideckeHRiemekastenGDragunDet al

Berberine is an isoquinoline alkaloid extracted from various plants including Berberis species (barberry), Coptis chinensis (goldthread), and Hydrastis canadensis (goldenseal)

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With this early rescue dose, the patient likely survives because the dashed black curve in Panel B stays well above the 30% level for functional hepatocytes, which is thought to indicate liver failure

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