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Many patients experience an average weight loss of 10% to 18% of their starting body weight, and some lose 15% to 21% of their body weight over 68 weeks, depending in part on starting weight
Soluble fractions were separated from denatured proteins by ultracentrifugation at 100,000 g and 4 C for 20 min (Beckman Coulter Optima MAX-XP, with TLA-120.1 rotor)
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The complete antibody list is provided in Supplementary table Antibody section
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Clinicians should be aware of potential interactions with narrow therapeutic index drugs that depend on rapid absorption (e.g., oral contraceptives, levothyroxine, warfarin) and may need to adjust timing or monitoring accordingly
