The objective of this review is to provide an update on the effectiveness of oral vitamin B12 for the treatment of pernicious anemia, the recommended dosage, and the required frequency of laboratory test and clinical monitoring
NLRC5 senses NAD(+) depletion, forming a PANoptosome and driving PANoptosis and inflammation
When we don't get enough vitamin B12, it can: Reduce ATP production, potentially contributing to mitochondrial dysfunction and insulin resistance Cause megaloblastic anemia, characterized by abnormally large, hemoglobin-poor red blood cells that die prematurely
We need to follow the latest research and guidelines
[32] Can injections be self-administered
[11] In practice, the benefit of treating a true B deficiency in pregnancy, preventing anemia and neurological injury, is considered to far outweigh any theoretical risks, under the guidance of a healthcare professional