Although extensive studies on the effects of exogenous GSH have been performed, results on the stress responses were still differential across different studies, particularly the variable response of the antioxidant enzymatic activities, where some studies reported a decrease in enzymatic activities albeit an increase in GSH/GSSG ratio (Goodarzi et al., 2020)
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[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency
Glutathione injections offer a practical way to restore these levels
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