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Different actions of intracellular zinc transporters ZIP7 and ZIP13 are essential for dermal development

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Finally, it aggregates into complexes with platelets, adheres distal to the primary tumor, extravasates through vascular endothelial cells and leaves the circulatory system, and colonizes and proliferates in new tissue sites to form secondary tumors

Melanocytes affected by oxidative stress (OS) trigger the activation of innate immunity through the secretion of exosomes, which contain damage-associated molecular patterns (DAMPs), especially heat shock protein 70 (HSP70)

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