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Special cells in the base layer of the skin help absorb and remove harmful UV rays

Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety

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When activated by ROS or electrophilic substances, Nrf2 exits Keap1 and moves to the nucleus, functioning as a transcription factor to enhance the production of subsequent antioxidant and detoxi-fying enzymes like HO-1, NAD (P)H, NQO-1, SOD, and GSH-PX (112, 113)

Peer review Peer review information Nature Cancer thanks Navdeep Chandel and Isaac Harris for their contribution to the peer review of this work