Phase 2 trial data (Jastreboff et al., NEJM, 2023) demonstrated substantial weight reduction participants lost a mean of approximately 24% of body weight over 48 weeks at the highest doses alongside improvements in cardiometabolic markers
NICE has approved specific GLP-1 receptor agonists (semaglutide [Wegovy] in TA875 and liraglutide [Saxenda] in TA664) for weight management in eligible patients, subject to NHS local prescribing criteria
For how Mounjaro compares with other medicines and how doses differ, see our Mounjaro vs Wegovy guide
The liquid itself As emphasized throughout this guide, the liquid inside any genuine Ozempic or Wegovy pen must be clear and colorless
The combination of copper peptides and retinol can cause irritation in sensitive individuals, though many people tolerate both when used at separate times
Scheen AJ (2019) SGLT2 inhibitor or GLP-1 receptor agonist in type 2 diabetes