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In this latest announcement, FDA reiterated its 2018 guidance while also clarifying its position on compounded GLP-1s combined with an additional API
Factors that influence adaptation speed include baseline gut motility (people who already had slower digestion may adapt faster because the change is less dramatic), diet composition, physical activity level, stress, and genetic variation in GLP-1 receptor sensitivity
Cruz-Gonzalez I, Corral E, Sanchez-Ledesma M, Sanchez-Rodriguez A, Martin-Luengo C, Gonzalez-Sarmiento R
Risk & Benefits GLP-1 agonists, used to lower blood sugar levels and promote weight loss, offer additional potential benefits (4)(6)
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