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Its the only antidepressant associated with weight loss rather than gain, and its used off-label for weight management
While clinical trials demonstrate benefits, GLP-1 therapies are also associated with adverse events
Tirzepatide works similarly on the GLP-1 receptor, but also binds to the GIP receptor as well
Its research relevance is upstream: it stimulates the GHRH receptor, leading to GH release and downstream endocrine effects
Fiber: your second priority Fiber does double duty on semaglutide
If it is used with insulin or a sulfonylurea, low blood sugar risk may increase, so other therapy amounts may need careful adjustment by the care team
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