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Mechanisms of cisplatin nephrotoxicity
Glutathione also helps maintain and regenerate other important antioxidants, including vitamins C and E the three nutrients even have a sparing effect on one another, filling in to keep levels of each close to optimal
In activated T cells, metabolic fitness and synthetic function has been directly linked to G6PD activity and ROS homeostasis by Ghergurovich and colleagues, who used a novel metabolite reporter and deuterium tracer assays to monitor cellular G6PD activity in the presence of a specific potent inhibitor of G6PD (55)
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