VIVUS is committed to advancing treatment options for obesity and offering much-needed hope to adult and pediatric patients globally
If blood osmolarity is too high, meaning that the blood is not dilute enough, osmoreceptors signal the hypothalamus to release ADH
This means that for a bioactive agent, like L-Carnitine, to exert its desired effect, it must be in physical contact with its physiological target
That includes: New once-weekly or even once-monthly injectable treatments
We performed this subgroup analysis for two reasons: 1) to eliminate the potentially confounding factor of using other diabetic medications such as metformin or insulin, and 2) we did not have data on the severity of diabetes such as hemoglobin A1c which may be an additional confounding factor
Why Formulation Design Matters To solve the problem of absorption, we utilize liposomal delivery