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Further studies are needed here, but it has the potential as a treatment for obesity and diabetes.[ref] EGCG: Found in green tea, EGCG has been shown in cell studies to increase GLP-1 secretion.[ref] Yerba mate tea: Animal studies show that Yerba mate induces GLP-1 secretion.[ref] Increase bitterness: The TAS2R38 gene, a bitter taste receptor, is active in the same cells in the gastrointestinal tract as glucagon-like peptide 1 cells

We conducted the literature search on PubMed and Embase (Ovid) in December 2023 and updated it in June 2024

SSTR5 activation strongly inhibits GLP-1 or GIP secretion by activating Gi signaling 19,20

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This observation indicates that, at a certain level, GSH application can partly reverse the mutant phenotype

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