Administration of semaglutide at the dose regimen of ~ 90 g/kg/day failed to evidence significant weight loss but more importantly, led to alteration of cortical bone microarchitecture, represented by lower cortical thickness, and ultimately to a significant decrease in bone strength [69]
And if heart health is on your mind, especially if you're menopause, then have a conversation with your clinician
For example, if your goal weight is 135 pounds, we recommend you eat 135g or protein per day to preserve lean muscle and support your metabolism
The Yale Journal of biology and medicine 48, 403407 (1975)
Without the drug, appetite returns
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