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How to choose the right concentration for your protocol The best concentration depends on where you are in your dosing schedule

These additives have no proven clinical benefit for patients taking tirzepatide, and the resulting combinations introduce unknown risks for patients

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18 The SYNERGY-NASH (A Study of Tirzepatide [LY3298176] in Participants With Nonalcoholic Steatohepatitis) trial, 19 a phase 2b dose-finding study, randomized 190 patients with biopsy-confirmed MASH and stage 2 or 3 fibrosis to receive weekly injections of the GLP-1 and GIP dual agonist tirzepatide 5 mg, 10 mg, or 15 mg or placebo for 52 weeks