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Red blood cells, white blood cells, and platelets make up the cellular component of blood

However, long-term risks such as rare adverse effects, metabolic effects over years, effects on bone, gallbladder, and pancreas need phase-3 trials and post-marketing surveillance to ensure the medication is safe for long-term use

[10] Rasmussen L, Poulsen CW, Kampmann U, Smedegaard SB, Ovesen PG, Fuglsang J

Interaction of IL-6 and TNF-alpha contributes to endothelial dysfunction in type 2 diabetic mouse hearts

This effect was mediated by cAMP and PKA and was absent in mice with genetic deletion of the GLP-1R (54)