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Oxalate in renal stone disease: the terminal metabolite that just wont go away
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Rapid weight loss has been a hallmark of these medications, which work, in part, by making users feel full earlier by activating receptors of hormones secreted from the intestine (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) to reduce appetite and food intake
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In the context of GLP-1R agonists, systemic exendin-4 robustly activates CGRP-expressing lPBN neurons, and its chronic weight-lowering effects are attenuated by their silencing [63]
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