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By 12 months post-stop, most patients have returned to within 10 to 20 percent of their starting weight

Egging D, van Vlijmen-Willems I, van Tongeren T, et al

Compounding may be appropriate when: A required dose, concentration, or formulation is not commercially available An FDA-approved drug is in a temporary shortage A patient has a documented allergy or intolerance to an inactive ingredient Compounding is intended to address medical necessity , not convenience, mass substitution, or price alone

10.1038/s41580-023-00629-4 90

Your body is becoming more efficient and is reacting to a lower calorie environment and a reduction in insulating fat