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All GLP-1RAs bind with specificity to the GLP-1 receptor and stimulate glucose dependent insulin release from the pancreatic beta cells (30)

In cell-based therapy, mesenchymal stem cells release a variety of bioactive factors through paracrine mechanisms, coordinating immune regulation, neuroprotection, and vascular remodeling, thereby modulating the functional balance of the immune-inflammatoryblood-brain barrier axis (211)

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A meta-analysis and systematic review

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