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However, because this product provides doses far above the daily nutritional requirements (for instance 100 mg of B vs an RDA of ~1.4 mg), its use in pregnancy must be carefully considered

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Notably, gross spending does not account for drug rebates, which are paid by drug manufacturers to states and are shared between the states and the federal government to offset the overall cost of prescription drugs under states Medicaid programs

B12 Interactions with Medications Commonly Used by Elderly Elderly patients frequently take multiple medications (polypharmacy), increasing the potential for drug interactions that may either reduce B12 absorption or alter its efficacy

These occur because vitamin B12 is essential for maintaining the protective sheath around nerves

Each lot is independently tested for identity, purity, and mass using HPLC and mass spectrometry