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While Ozempic effectively manages blood sugar levels in type 2 diabetes, its mechanism of action, which involves slowing gastric emptying as part of its glucose-lowering effect, could lead to patients developing gastroparesis

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The Synergy Hypothesis Others believe the magic is specifically in the combination

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We find that a licensed GLP-1 receptor agonist modulates epigenetic biomarkers of aging, positioning semaglutide as a candidate gerotherapeutic and laying the groundwork for prospectively powered, mechanism-focused trials aimed at extending healthspan in populations vulnerable to accelerated aging