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In some tissues, such as that of liver, heart, and kidney, mitochondrial glycerol-3-phosphate dehydrogenase (GPD2) is present in very low amounts, and the malate-aspartate shuttle is the dominant pathway for aerobic oxidation of cytosolic NADH

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Refined carbohydrates, sugary beverages, and alcohol should be minimized because they offer empty calories without satiety and can trigger blood sugar swings and gastric upset

The tissue has had enough time to undergo cellular turnover and strengthening

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Managing Side Effects on the 0.5 mg Dose Whether you started at 0.25 mg or were one of the rare cases started at 0.5 mg, managing side effects is key to staying on track