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Indole-3-lactic acid associated with bifidobacterium-dominated microbiota significantly decreases inflammation in intestinal epithelial cells

Discussing this with biotech/pharma sponsors and building some dose escalation buffer into a protocol to keep the participant in the study and manage these AEs (when possible) can be a good strategy to keep participants in the trial & improve their experience

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One key reason is that proper thyroid function depends on more than just medication - it requires the right nutrients, particularly amino acids, to support thyroid hormone conversion

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