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Effect of various dosing schedules on the pharmacokinetics of oral semaglutide: a randomised trial in healthy subjects

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At the expected therapeutic dose of 0.5mg, the discontinuation rate due to side effects was similar to that of the placebo group (32%).In another trial called TIPO-2, which lasted for 14 days, tesofensine was found to reduce the desire to eat and increase feelings of fullness in obese patients

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