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Phys Chem Chem Phys
Transport of glutathione, glutathione disulfide, and glutathione conjugates across the hepatocyte plasma membrane
Sublingual troches: Typical dose: 50-200mcg per troche Frequency: 1-2 times daily Administration: Dissolve between cheek and gum for 15-20 minutes Absorption: Bypasses first-pass liver metabolism through oral mucosa Liposomal oral: Typical dose: 100-500mcg Frequency: Once daily Note: Lipid encapsulation protects peptide through digestion Oral forms suit those unwilling to inject who still want systemic rather than purely local effects
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This dual mechanism establishes RBIDF as an effective dietary intervention against cadmium-induced damage (134)
