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In real-world studies, GLP-1 RAs have consistently been associated with reduced cardiovascular risk in people with T2D [23,24,25,26,27,28], including reduced incidence of stroke (HRs between 0.65 and 0.74) and MI (HRs between 0.63 and 0.86)

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S., Elizondo-Fraire, A

[12] Adverse effects [edit] Preclinical, phase I, and phase II clinical trials indicated that tirzepatide exhibits adverse effects similar to those of other established GLP-1 receptor agonists, such as dulaglutide (sold as Trulicity) and semaglutide (sold as Wegovy, Ozempic, and Rybelsus)