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Behaviorally, the LAC treatment during the last part of chronic restraint stress (CRS) enhanced resilience and reversed the effect of CRS, which is shown by increased social interaction and reduced passive behavior in a forced swim test (82)

Os autores ressaltam, porm, que os achados ainda so preliminares e dependem de novos estudos clnicos em humanos

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Observed physiological responses vary depending on study duration, metabolic status, and experimental design

(2016) found that acute fluoxetine administration in prepubertal female rats resulted in increased estradiol concentrations, whereas subchronic administration led to increased serotonin concentrations in the ovaries, a decrease in the number of ovulations, a greater number of atretic follicles, and oocyte fragmentation