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These factors can impact how each drug affects weight loss and overall health issues
While a generic company must engage in a costly and lengthy legal battle to challenge a patent, a 503B facility might be able to legally compound a version of that same drug if it appears on the shortage list, completely bypassing the Hatch-Waxman framework
The rate of dropout in studies of oral semaglutide has been significant, approximately 25% in recent trials, reflecting tolerability concerns, mainly due to nausea (source)
However, certain individuals may need alternative pathways such as those with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2
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