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Some individuals are genetically predisposed to melasma, and are more likely to develop age spots later in life

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Synthesis of phosphatidylcholine The figure illustrates the cytidine diphosphate (CDP)-choline pathway for phosphatidylcholine synthesis, showing chemical structures of intermediates and involved enzymes

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4.1 Evidence from epidemiological and clinical studies Large-scale human studies have consistently demonstrated robust associations between EED exposure and deterioration in fundamental reproductive parameters, including sperm concentration, motility, and DNA integrity

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