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Less common but notable side effects, such as hair loss, depression, or serious gastrointestinal symptoms, should be monitored closely
It enhances both synthesis and breakdown of extracellular matrix components, such as collagen, glycosaminoglycans (including dermatan and chondroitin sulfate), and decorin, and regulates metalloproteinases and their inhibitors (Pickart, Vasquez-Soltero, and Margolina 2015)
Many patients starting semaglutide pursue collagen for skin elasticity and joint support during weight loss
However, very high concentrations can also be irritating
PubMed , European Journal of Clinical Pharmacology , vol
