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Challenges in Drug Delivery Across the BloodBrain Barrier The BBB is defined by the specialized structure of brain microvasculature, characterized by TJs, limited vesicular transport, and minimal fenestration, all of which tightly regulate molecular exchange between blood and brain [42]

At the molecular level, their mechanisms complement each other

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Vitamin C Vitamin C is a water-soluble nutrient, which means it can't be stored in the body for later use

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