These groups include: Vegetarians and Vegans: Because plant-based diets lack natural sources of B12, supplementation is often necessary to prevent deficiency-related symptoms such as fatigue, anaemia, and nerve damage
When people rapidly lose lots of weight, they can also lose muscle mass, a particular concern for older patients, Yanovski says
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They also carry a lower risk of hypoglycemia compared with insulin and have demonstrated cardiovascular safety and benefits
10.1210/jc.2017-00346 100 LiH.LiuF.WangX.LiM.LiZ.XieY.et al (2021)