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The primary goal was to assess the impact of tirzepatide compared to the placebo on the change in clamp disposition index, which combines measures of insulin secretion and sensitivity
demonstrated a significant reduction in pigment intensity and melasma area in almost 80% of Chinese patients taking the drug (25 mg thrice daily for 30 days)
Subjective results (sleep, energy, recovery) begin within 2-3 weeks
it's a fundamental principle of safety
doi:10.1007/s11064-010-0217-0
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