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Lack of robust human clinical trials prevents confirmation of consistent outcomes, optimal dosing, or long-term safety
That said, patients with active diabetes or significant metabolic dysfunction should have any investigational peptide protocol reviewed by their endocrinologist or primary care physician alongside their supervising aesthetic medicine provider
Cartilage & Joint Research Kwon and Park, Annals of Clinical and Laboratory Science (2015) Kwon and Park investigated the chondroprotective effects of intra-articular AOD-9604 administration in a rabbit model of osteoarthritis, with and without co-administration of hyaluronic acid
The experiments were performed according to the criteria of the new investigational drug application
This enzyme is overactive in individuals with excess abdominal fat and metabolic dysfunction
The legal status of peptides in the UK (such as BPC-157, MK-677 etc) can appear slightly unclear
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