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Cytochrome P450-mediated metabolism of estrogens and its regulation in human

This, in turn, triggers the HIF1A (hypoxia inducible factor 1 subunit alpha)-dependent Warburg effect and AIM2 (absent in melanoma 2)-dependent inflammasome activation, contributing to Kras G12D -induced pancreatic tumorigenesis [212]

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2016;113:E1738E1746