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Consequently, a significant proportion of administered nanocarriers is prematurely sequestered and cleared by the reticuloendothelial system (RES)particularly the liver and spleensubstantially limiting the effective dose that reaches the osteosarcoma TME (69, 70)
It is closely associated with choline
used angiotensin (Ang) II injection to simulate a hypertension-mediated cardiac remodeling model and found that ferroptosis occurred and that the protein expression of GPX4 and xCT was downregulated in the myocardium
Bronchoalveolar lavage (BAL) was performed in 64 asthmatic children (severe asthma, n = 43)
Marked improvement in objective function tests was achieved after three cycles of ozone therapy (Table IV)
On the other hand, substantial downregulation of GCLC, the ratelimiting enzyme of GSH synthesis, is consistent with our hypothesis that GSH synthesis is impaired in tumors
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