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A randomized, double-blind, placebo-controlled in 129 young healthy adults found that taking a supplement that contained ten times the daily intake recommendations for nine different vitamins (vitamin A, thiamin, riboflavin, niacin, vitamin B 6 , folic acid, vitamin B 12 , vitamin C, vitamin E) for one year improved one self-assessment of mood, i.e., being more agreeable (137)

Nat Rev Dis Primers 5(1):118

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For example, once weekly dosing of tirzepatide (a dual GIPR and GLP-1R co-agonist) has superior efficacy for weight reduction compared to the GLP-1R agonist, semaglutide

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