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Despite their effectiveness, they come with a range of potential side effects that can impact patient comfort and adherence to treatment
This damage is called endothelial dysfunction
doi:10.1016/j.foodchem.2013.05.017
Historically, the liver has been acknowledged as the main location where metformin reduces glucose levels, however, there is increasing evidence suggesting that the gastrointestinal tract also plays a significant role in its action
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