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[13] In the first step of the reaction, acyl-CoA synthetase catalyzes the transfer of adenosine monophosphate group (AMP) from an ATP molecule onto the fatty acid generating a fatty acyladenylate intermediate and a pyrophosphate group (PP i )
Neggers et al., confirmed these observations, highlighting that over 70% of children affected by ASD showed positivity to these autoantibodies and may benefit from targeted folinic acid supplementation (Neggers, 2014
This opinion is supported by a study showing activity-driven ATP production at axon terminals [57]
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