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Mice carrying null mutations of the genes encoding insulin-like growth factor I (IGF-I) and type 1 IGF receptor (Igf1r)

Lange G, Lin JS, Chen Y, Fall EA, Peterson DL, Bateman L, et al

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In old rats with OVX-induced osteoporosis, exendin-4 decreased the concentration of C-terminal cross-linked telopeptides of type I collagen (CTX-1) and the urinary deoxypyridinoline (DPD)/creatinine ratio (31)