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Not everyone experiences this side effect, and the severity can vary greatly between individuals

Some believe this could be the case with IGF-1, but others argue that supplementing with it comes with several harmful side effects

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Renal Impairment In clinical trials [see Clinical Studies ] a total of 75 (7%) of the 1102 TRESIBA treated patients with type 1 diabetes had an eGFR less than 60 mL/min/1.73 m 2 and 1 (0.1%) had an eGFR less than 30 mL/min/1.73 m 2

Absolute risks are relatively low, but worth understanding before starting, especially for lifelong use

doi:10.1016/S0891-5849(02)01360-6