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Any discomfort is easily treated with over-the-counter pain medication, allowing patients to jump back into their activities without hesitation

Statistical analysis was performed in GraphPad Prism 7 using one-way analysis of variance (ANOVA) for comparison followed by Dunnetts multiple comparison test where applicable

Orforglipron is the first small molecule GLP-1 to complete a Phase III trial, lowering A1C by an average of 1.3% to 1.6% across doses

13 However, the clinical relevance of these mechanistic advantages in adolescent populations remains uncertain due to the absence of robust pediatric data

Pain triggers sympathetic activation, leading to tachycardia, hypertension, increased myocardial oxygen demand, and a surge in stress hormones

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