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Common side effects include: Nausea (Most Common) Affects approximately 40% of users Usually occurs within 1-2 hours of administration Typically resolves within 2-4 hours Taking with light food may help reduce severity Facial Flushing Temporary redness or warmth in face and neck Usually mild and subsides within a few hours Result of increased blood circulation Mild Headache Generally less severe than with PDE5 inhibitors Often resolves without treatment Staying hydrated may help prevent the occurrence Nasal Congestion Temporary stuffy nose sensation Less common than with traditional ED medications Usually clears within a few hours Important Safety Considerations Cardiovascular Effects PT-141 may cause a temporary, mild increase in blood pressure

Specific PK/PD data for liraglutide and warfarin were not identified [37]

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10.1007/s00405-021-06628-5 39 LeeH