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10.1097/ICO.0b013e31821dd986 143 TurkovicB.SikiricP.SeiwerthS.MiseS.AnicT.PetekM.et al (2004)
A rare but serious adverse event is lactic acidosis, especially in patients with organ dysfunction or failure, necessitating careful monitoring and dosage adjustments in these populations
Practical signs to track Puffiness around the eyes or ankles on waking Ring or shoe tightness that wasn't there before Scale weight up 1-3 kg in the first two weeks with no dietary change Reduced visual definition despite no change in body fat None of these alone confirm a problem, but tracking them against a personal baseline separates normal early-adaptation fluid shift from a genuine signal to drop your dose
Final word from Endocare The arrival of effective oral GLP-1 medications is a real shift in weight-loss medicine, and a useful one
They can lead to unconscious air swallowing and can alter gut motility
Are weight-loss drugs raising your heat wave risks
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