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PMID: 26308095

If you develop these symptoms while taking tirzepatide, contact your primary care doctor or visit urgent careearly detection prevents serious complications like cholecystitis or pancreatitis

**Diarrhea or Constipation**: Patients may experience changes in bowel habits

Although how exactly these drugs help in weight loss is not known, as GLP-1 agonists slow the movement of food traveling from the stomach to the small intestine, it makes people feel full quicker and for longer, and so, it is thought to boost weight loss because people tend to eat less as result of the medication

If you experience persistent constipation (a risk with slowed gastric motility), increase fiber and water intake gradually, and discuss stool softeners with your doctor

Practice double voiding (urinating twice to empty the bladder fully)